방사성동위원소를 이용한 Gastric Emptying Time의 연구

Gastric Emptying Time (GET) Test Using Radioisotope

  • 구본환 (경북대학교 의과대학 핵의학교실) ;
  • 하승우 (경북대학교 의과대학 핵의학교실) ;
  • 손상균 (경북대학교 의과대학 핵의학교실) ;
  • 이재태 (경북대학교 의과대학 핵의학교실) ;
  • 이규보 (경북대학교 의과대학 핵의학교실) ;
  • 황기석 (경북대학교 의과대학 핵의학교실)
  • Koo, Bon-Hwan (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Ha, Sung-Woo (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Son, Sang-Kyun (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Jae-Tae (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Kyu-Bo (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Whang, Kee-Suk (Department of Nuclear Medicine, School of Medicine, Kyungpook National University)
  • 발행 : 1988.11.25

초록

A gamma camera coupled to a computer was used in 20 normal volunteers after ingestion of the mixture of $^{99m}Tc-DTPA$ and milk in order to determine gastric emptyng time (GET) and to evaluate the effect of metoclopramide, a dopamine antagonist that stimulates gastric motility, to gastric emptying. The normal value for biological gastric emptying half time was found to be $63{\pm}7$ minutes, and the gastric emptying was monoexponential fashion, at least for the first 60 minutes. Among the 20 volunteers, nine were repeated the test after injection of metoclopramide, which has significantly reduced the value of GET to $31{\pm}3$ minutes (p<0.01). GET test using $^{99m}Tc-DTPA$ is very useful in gastric function evaluation, especially in follow-up check of the functional change.

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