대한핵의학회지 (The Korean Journal of Nuclear Medicine)

대한핵의학회 (The Korean Society of Nuclear Medicine)
권호 표지

항갑상선제로 치료받은 Graves병 환자에서 수술시 갑상선 정맥혈과 말초정맥혈간에 TSH 수용체항체의 활성도에는 차이가 없다

There is no Gradient of TSH Receptor Antibody Activity Between Thyroidal and Peripheral Venous Blood in Patients with Graves' Disease, Undergoing Subtotal Thyroidectomy, Prepared with Antithyroid Drugs

  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 송영기 (서울대학교 의과대학 내과학교실) ;
  • 조보연 (서울대학교 의과대학 내과학교실) ;
  • 궁성수 (서울대학교 의과대학 내과학교실) ;
  • 이명혜 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 오승근 (서울대학교 의과대학 외과학교실)
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Shong, Young-Kee (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Cho, Bo-Youn (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koong, Sung-Soo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Hae (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Oh, Seung-Keun (Department of General Surgery, College of Medicine, Seoul National University)
  • 발행 : 1988.11.25
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초록

Thyrotropin binding inhibitory immunoglobulin (TBII) and thyroid stimulating antibody (TSAb) activities were measured in the thyroidal and peripheral venous blood samples at the time of subtotal thyroidectomy from twenty one patients with Graves' disease prepared for surgery with antithyroid drugs. There was no difference in TBII and TSAb activities between thyroidal and peripheral blood samples. These findings were regarded that while intrathyroidal lymphocytes are major site of thyrotropin receptor antibody (TRAb) production, similar levels are found in thyroidal and peripheral veins and that this in vivo study cannot exactly ascertain the TRAb producing site.

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