The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Studies on the Regional Cerebral Blood Flow in Delayed Carbon Monoxide sequelae using $^{99m}Tc-HMPAO$

지연성 일산화탄소중독후유증 환자에서 $^{99m}Tc-HMPAO$를 이용한 국소 뇌혈류량의 SPECT소견

  • Ahn, Jae-Hoon (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Lee, Do-Yun (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Kim, Jin-Soo (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Suh, Jung-Ho (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Kim, Dong-Ik (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Lee, Myung-Sik (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Chung, Tae-Sub (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Park, Chan-H. (Division of Nuclear Medicine, Thomas Jefferson University Hospital)
  • 안재훈 (연세대학교 의과대학 진단방사선과학교실) ;
  • 이도연 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김진수 (연세대학교 의과대학 진단방사선과학교실) ;
  • 서정호 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김동익 (연세대학교 의과대학 진단방사선과학교실) ;
  • 이명식 (연세대학교 의과대학 진단방사선과학교실) ;
  • 정태섭 (연세대학교 의과대학 진단방사선과학교실) ;
  • 박찬희 (미국 Thomas Jefferson 의과대학 핵의학교실)
  • Published : 1988.11.25
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Abstract

8 patients of delayed CO sequelae were evaluated using Brain CT and $^{99m}Tc-HMPAO$ SPECT. The results were as follows; 1) CT findings of delayed CO sequleae were bilateral low density lesion in globus pallidus (l pt.), diffuse low density in white matter with bilateral low density in white matter (l pt.), diffuse low density in white matter with bilateral low density in globus pallidus (l pt.), diffuse low density in white matter with cortical atrophy (l pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (l pt.) and normal in 3 pts. 2) $^{99m}Tc-HMPAO$ Brain SPECT findings of delayed CO sequelae were decreased regional cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) $^{99m}Tc-HMPAO$ Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

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