Bulletin of the Korean Chemical Society

  • 제9권6호
  • /
  • Pages.341-345
  • /
  • 1988
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
권호 표지
DOI QR코드

DOI QR Code

Separation of Optical Isomers of Amino Acids with Addition of Benzyl-L-proline Copper (II) Chelate by Reversed Phase Liquid Chromatography

  • Lee, Sun-Haing (Department of Chemistry, Kyungpook National University) ;
  • Oh, Dae-Sub (Department of Chemistry, Kyungpook National University) ;
  • Kim, Byoung-Eog (Department of Chemistry, Kyungpook National University)
  • 발행 : 1988.12.20
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Separation of optical isomers of dansyl amino acids by a reversed phase liquid chromatography has been accomplished by adding a copper (II) chelate of N-benzyl-L-proline to the mobile phase. The pH, the eluent composition and the concentration of copper (II) chelate all affect the optical separations. The elution orders between D and L DNS-amino acids were consistant except dansyl phenylalanine showing that D forms of DNS-amino acids elute earlier than L forms. These behaviors are different from the results obtained by the use of copper (II) proline. The retention mechanism for the optical separation of the dansyl amino acids can be explained by the equilibrium of liqand exchange and by hydrophobic interaction.

키워드

참고문헌

  1. Chem. Lett. Y. Yuki;K. Saigo;K. Tachihana;M. Hasegawa
  2. J. Liq. Chromatogr. v.9 B. Bomgren;S. Allenmark
  3. J. Chromatogr. v.351 M. J. B. Lloyd
  4. J. Liq. Chromatogr. v.8 D. Charmot;R. Audebert;C. Quivoron
  5. J. Chromatogr. v.348 H. Berndt;G. Kruger
  6. J. Chromatogr. v.285 N. Qi;H. Kithara
  7. J. Chromatogr. v.261 A. V. Kurganov;A. B. Tevlin;V. A. Davankov
  8. J. Chromatogr. v.260 N. Watanabe
  9. J. Chromatogr. v.218 V. A. Davankov;A. S. Bochkov;Y. P. Belov
  10. J. Chromatogr. v.186 S. Hara;A. Dobashi
  11. J. Chromatogr. v.216 N. Watanabe;H. O. Ohzeki;E. Niki
  12. J. Amer. Chem. Soc. v.97 G. Dotsevi;Y. Yogah;D. J. Cram
  13. J. Chromatogr. v.185 A. Foucault;M. Caude;L. Oliveros
  14. J. Chromatogr. v.141 V. A. Davankov;A. V. Semechkin
  15. Anal. Chem. v.60 R. E. Boehm;D. E. Martire;D. W. Armstrong
  16. Chromatographia v.21 H. Engelhardt;T. Konig;S. Kromidas
  17. J. Chromatogr. v.363 Y. Okamoto;M. Kawashima;K. Hatada
  18. Anal. Chem. v.57 D. W. Armstrong;W. DeMond;B. P. Czech
  19. J. Amer. Chem. Soc. v.102 E. Gil-Av;A. Tishbee;P. E. Hare
  20. J. Chromatogr. v.368 S. Lam;G. Malikin
  21. J. Chromatogr. v.357 T. Takeuchi;H. Asai;D. Ishii
  22. J. Chromatogr. v.355 S. Lam
  23. J. Chromatogr. Sci. v.23 R. Wernicke
  24. J. Chromatogr. v.331 T. Takeuchi;H. Asai;Y. Hashimoto;K. Watanabe;D. Ishii
  25. Anal. Chem. v.56 M. H. Engel;S. A. Macko
  26. J. Chromatogr. v.316 N. Nimura;A. Toyama;T. Kinoshita
  27. J. Chromatogr. v.255 S. Lam;A. Karmen
  28. J. Chromatogr. v.255 E. Grushka;R. Leshem;C. Gilon
  29. J. Chromatogr. v.205 Y. Tapuhi;N. Miller;B. L. Karger
  30. J. Chromatogr. v.203 C. Gilon;R. Leshem;E. Grushka
  31. Anal. Chem. v.52 C. Gilon;R. Leshem;E. Grushka
  32. J. Korean Chem. Soc. v.30 S. H. Lee;T. S. Oh;K. S. Park
  33. Bull. Korean Chem. Soc. v.7 S. H. Lee;J. W. Ryu;K. S. Park
  34. Anal. Chem. v.51 J. N. Lepage;W. Lindner;G. Davies;D. E. Seitz;B. L. Karger
  35. Chemical Derivatization in LC J. F. Lawrence;R. W. Frei
  36. J. C. S. Dalton V. A. Davankov;P. R. Nitchell