Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthsis of N-Phenylcysteine

  • Published : 1988.02.20
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Abstract

N-Phenylcysteine (1) was prepared as a hydrobromide in good yield from the acid hydrolysis of 4-carboxy-2-methyl-3-phenyl-${\Delta}^\;2$-thiazolinium bromide (5), which was derived from the reaction of thioacetanilide and $\alpha$ -bromoacrylic acid. The treatment of ethyl ester(6) of N-phenylcysteine with 2,2-dimethoxypropane rendered it to ethyl 2,2-dimethyl-3-phenylthiazoline-4-carboxylate (7).

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References

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