Journal of Food Hygiene and Safety (한국식품위생안전성학회지)
- Volume 3 Issue 3
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- Pages.111-116
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- 1988
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
Antitumor Activity of Protein-Plysacharides Produced form Vibrio anguillarum
- Yu, Byeong-Ho (Department of Food science and Technology, Kyung-Sung University) ;
- Chi, Boung-Ho (Department of Food science and Technology, Kyung-Sung University) ;
- Kim, Dong-Suck (Department of Food science and Technology, Kyung-Sung University) ;
- Jang, Mi-Kyung (Department of Food science and Technology, Kyung-Sung University) ;
- Kim, Hae-Sung (Department of Food science and Technology, Kyung-Sung University) ;
- Chung, Soo-Ja (Department of Food and Nutrition, Pusan Woman's Junior College)
- Published : 1988.09.01
Abstract
The antitumor activity of protein-polysaccharide produced by a strain, Vibrio anguilfarum, No. 17 isolated from sea water was investigated. The extracellular protein,polysaccharide used in this experiment was obtained through the cultivation of Vibrio anguillarum No. 17 at
해수로부터 분리 확인한 비브리오균에서 생산하는 단백 다당체의 항종양 활성에 대하여 조사하였다. 비브리오균을 0.5%-peptone와 0.5% yeast extract가 함유된 해수를 기질로 배양하여 단백 다당체를 얻었다. 단백다당체의 단당류의 함량은 xylose, mannose, galactose, glucose 및 fructose의 순서이고, 주요 아미노산 glutamic acid, serine 및 aspartic acid였다. 단백 다당체의 항종양 활성을 Sarcoma-180에 대하여 0.5mg/kg/day 및 5mg/kg/day을 쥐에 주사했던 바 20.9% 및 43.9%의 억제 효과가 있었다.