Radiation Oncology Journal

The Korean Society for Radiation Oncology (대한방사선종양학회)
권호 표지

Total Body Irradiation in Leukemia - Preliminary Report -

방사선 전신조사

  • Jang Hong Seok (Department of Radiology, Cartholic University Medical College) ;
  • Chung Su Mi (Department of Radiology, Cartholic University Medical College) ;
  • Choi Ihl Bohng (Department of Radiology, Cartholic University Medical College) ;
  • Kim Choon Yul (Department of Radiology, Cartholic University Medical College) ;
  • Bahk Yong Whee (Department of Radiology, Cartholic University Medical College) ;
  • Kim Choon Choo (Department of Internal Medicine, Catholic University Medical College) ;
  • Kim Dong Jip (Department of Internal Medicine, Catholic University Medical College) ;
  • Lee Jae Soo (Department of Radiation Oncology, Yonsei University College of Medicine)
  • 장홍석 (가톨릭의대 성모병원 방사선과학교실) ;
  • 정수미 (가톨릭의대 성모병원 방사선과학교실) ;
  • 최일봉 (가톨릭의대 성모병원 방사선과학교실) ;
  • 김춘열 (가톨릭의대 성모병원 방사선과학교실) ;
  • 박용휘 (가톨릭의대 성모병원 방사선과학교실) ;
  • 김춘추 (가톨릭의대 성모병원 내과학교실) ;
  • 김동집 (가톨릭의대 성모병원 내과학교실) ;
  • 이재수 (가톨릭의대 성모병원 내과학교실)
  • Published : 1988.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

Total body irradiation has been applied to treat acute leukemia and chronic granulocytic leukemia.20 patients with acute leukemia or chronic granulocytic leukemia were treated with total body irradiation using 6 MV linear accelerator before bone marrow transplantation at the Division of Therapeutic Radiology, Department of Radiology, St. Mary's Hospital, Catholic University Medical College from August 1987 to September 1988. Among 20 patients, 8 patients received 6 fractions of 200 cGy (total 1200 cGy),10 patients received a single 850 cGy radiation,1 patient received 4 fractions totalling 850 cGy (200, 200, 200, 250), and 1 patient received 1100 cGy in 2 fractions (850, 250).17 patients received allogenic grafts, 2 patients received autologous grafts, and only one patient received one locus mismatched graft. 13 patients are still alive and 7 patients died. The complications induced by total body irradiation were nausea and vomiting, diarrhea, skin erruption, mucositis, and pneumonitis.

1987년 8월부터 1988년 월까지 가톨릭의대 부속 성모병원 방사선과에서는 20명의 급성 백혈병 환자와 만성과립성 백혈병 환자를 6MV선형가속기를 사용하여 전신조사 하였다. 20명의 환자 중 8명은 총 방사선량 1200cGy책 1회 방사선 조사를 받았다. 나머지 2명 중 1명은 4회 분할 조사로 총 850cGy를 받았으며, 다른 1명은 2회 분할 조사하여 총 1100cGy를 받았다. 이식편은 20명중 17명이 동종 이식편을 받았고, 2명이 자가 이식편을 받았으며, 오직 1명만이 부적합 이식편을 받았다. 현재 13멍이 생존해 있고, 7명이 사망했으며, 전신조사에 의한 합병증은 설사, 점막염증, 구토와 구역, 피부발진 등의 순으로 나타났다.

Keywords