Radiation Oncology Journal
- Volume 6 Issue 2
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- Pages.169-176
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- 1988
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
Radiation Therapy of Suprasellar Germ Cell Tumors
뇌하수체상부 배아세포종의 방사선치료 성적
- Park Woo Yoon (Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
- Choi Doo Ho (Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
- Choi Eun Kyung (Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
-
Kim Il Han
(Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
- Ha Sung Whan (Department of Therapeutic Radiology, College of Medicine, Seoul National University) ;
-
Park Charn Il
(Department of Therapeutic Radiology, College of Medicine, Seoul National University)
- 박우윤 (서울대학교 의과대학 치료방사선과학교실) ;
- 최두호 (서울대학교 의과대학 치료방사선과학교실) ;
- 최은경 (서울대학교 의과대학 치료방사선과학교실) ;
-
김일한
(서울대학교 의과대학 치료방사선과학교실) ;
- 하성환 (서울대학교 의과대학 치료방사선과학교실) ;
-
박찬일
(서울대학교 의과대학 치료방사선과학교실)
- Published : 1988.12.01
Abstract
A retrospective study was performed on 15 patients with suprasellar germ cell tumors treated by megavoltage external beam irradiation between Feb. 1979 and Dec. 1985. Follow-up period of survivors was 30 to 91 months. Histologic diagnosis was obtained before radiation therapy in 10patients (9 germinomas and 1 mixed). Five patients were treated without histologic verification. In 9 patients with biopsy-proven germinomas radiation therapy was delivered to the craniospinal axis in 6, to the whole brain in 3. In 5 patients with mixed germ cell tumor or elevated tumor marker, irradiation was delievered to the craniospinal axis in 2, to the whole brain in 2, and to the primary site only in 1. Total doses ranged from 5,000 to 5,500 cGy to the primary site, 3,000 to 4,400 cGy to the whole brain, and 1,300 to 3,000 cGy to the spine. In these 14, local tumor was controlled and primary or spinal failure was not observed. One patient without elevated tumor marker was treated to the whole brain. The tumor was not controlled and he had spinal recurrence. Overall survival and disease-free survival rates were
1979년부터 1985년까지 서울대학교병원 치료방사선과에서 외부 방사선조사를 시행한 15명의 뇌하수체상부 배아세포종(전이송과선종) 환자에 대한 후향적 분석을 시행하였다. 생존자의 추적기간은