Journal of Pharmaceutical Investigation
- 제18권4호
- /
- Pages.175-180
- /
- 1988
- /
- 2093-5552(pISSN)
- /
- 2093-6214(eISSN)
지속 방출형 염산에탐부톨 마이크로캅셀의 제조에 있어서 스테아린산알루미늄의 효과
Effects of Aluminum Tristearate in the Preparation of Sustained Release Ethambutol Hydrochloride Microcapsules
- 유봉신 (숙명여자대학교 약학대학)
- Yoo, Bong-Shin (College of Pharmacy, Sookmyung Women's University)
- 발행 : 1988.12.20
초록
The role and effect of aluminum tristearate in microencapsulation were investigated based on the dispersion system of ethambutol hydrochloride in acetone-liquid paraffin. Eudragit RS was used as a wall-forming material. Eudragit RS microcapsules prepared using aluminum tristearate were uniform, free-flowing particles. The phase diagram of ethambutol hydrochloride-Eudragit RS-aluminum tristearate indicated that spherical microcapsules ranging from 250 to 1400
키워드