대한약리학회지 (The Korean Journal of Pharmacology)
- 제24권1호
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- Pages.103-109
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- 1988
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- 0377-9459(pISSN)
흰쥐 적출 자궁의 수축 작용과 흰쥐 장관에 있어 칼륨에 의해 활성화되는 칼슘 채널에 대한 Cyclobuxine D의 영향
Effects of Cyclobuxine D on Drug-Induced Contractions of the Isolated Rat Uterine Muscle and Potassium-Activated Calcium Channels in an Intestinal Smooth Muscle
- 권준택 (순천향대학 의학부 약리학교실) ;
- 이종화 (순천향대학 의학부 약리학교실) ;
- 박영현 (순천향대학 의학부 약리학교실) ;
- 조병현 (순천향대학 의학부 약리학교실) ;
- 최규홍 (순천향대학 의학부 약리학교실) ;
- 김유재 (순천향대학 의학부 약리학교실) ;
- 김종배 (순천향대학 의학부 약리학교실) ;
- 김정목 (순천향대학 의학부 약리학교실) ;
- 김천숙 (순천향대학 의학부 약리학교실) ;
- 차영덕 (순천향대학 의학부 약리학교실) ;
- 김영석 (순천향대학 의학부 약리학교실)
- Kwon, Jun-Tack (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Lee, Jong-Hwoa (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Park, Young-Hyun (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Cho, Byung-Heon (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Choi, Kyu-Hong (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Kim, Yu-Jae (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Kim, Jong-Bae (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Kim, Chung-Mok (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Kim, Chun-Sook (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Cha, Young-Deog (Department of Pharmacology, College of Medicine, Soonchunhyang University) ;
- Kim, Young-Suk (Department of Pharmacology, College of Medicine, Soonchunhyang University)
- 발행 : 1988.06.30
초록
Buxus microphylla var. koreana Nakai에 존재 하는 steroidal alkaloid인 cyclobuxine D는 흰쥐에 있어 심박동수 감소 작용, 적출 개구리 심장에서 수축력 감소작용, 토끼 적출 장관에서 acetylcholine과
Cyclobuxine D, extracted from Buxus microphylla var. koreana Nakai, is a steroidal alkaloid. Many pharmacological effects of cyclobuxine D were examined in our Lab. Cyclobuxine D showed a significant bradycardic effect in the rat heart and an inhibitory action on acetylcholine and