The Journal of Korean Academy of Prosthodontics (대한치과보철학회지)

The Korean Academy of Prosthodonitics (대한치과보철학회)
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A Study on the Toxicity of Several Dental Casting Alloys

수종(數種) 치과주조용(齒科鑄造用) 금속(金屬)의 독성(毒性)에 관(關)한 연구(硏究)

  • Kim, Gi-Jin (Dept. of Prosthodontics, School of Dentistry, Chon Buk National University) ;
  • Park, Charn-Woon (Dept. of Prosthodontics, School of Dentistry, Chon Buk National University)
  • 김기진 (전북대학교 치과대학 보철학교실) ;
  • 박찬운 (전북대학교 치과대학 보철학교실)
  • Published : 1987.12.01
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Abstract

This study was performed to investigate the biocompatibility of several dental casting alloys (Gold, Dong Myung A-45, Dong Myung AP-35, Verabond, Rexillium, NPG) employing tissue culture. Fibroblast-like cells derived from the subcutaneous tissue of Sprague-Dawley rat were cultivated in DME medium with the addition of those alloys. Results were assessed by calculating the cell multiplication rate and relative growth rate and by observing the morphology of cells in the presence of the specimens. Gold was indicated to be most biocompatible with fibroblast-like cell. Dong Myung A-45 and Dong Myung AP-35 showed very similar effects on the cells as did Gold. Also there was a decrease in cytotoxicity of the alloys as the concentration of gold increased. Verabond and Rexillium showed a decreased in cell mutiplication rate as compared to low gold alloys. NPG exhibited the most severe cell toxicity among the tested alloys.

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