Determination of Cholinesterase Activities in Sera of Human and Different Species of Animals by Means of the Propionylthiocholine-Dithiobis Procedure

Propionylthiocholine-Dithiobis 방법에 의한 사람과 몇몇 동물 혈청내의 Cholinesterase 활성도 측정

  • Kim, Soon-tae (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University) ;
  • Kim, Sung-hoon (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University) ;
  • Do, Jae-cheul (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University) ;
  • Lee, Young-ho (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University) ;
  • Mo, Ki-cheul (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University) ;
  • Huh, Rhin-sou (Department of Veterinary Medicine, College of Agriculture, Kyungpook National University)
  • 김순태 (경북대학교 농과대학 수의학과) ;
  • 김성훈 (경북대학교 농과대학 수의학과) ;
  • 도재철 (경북대학교 농과대학 수의학과) ;
  • 이영호 (경북대학교 농과대학 수의학과) ;
  • 모기철 (경북대학교 농과대학 수의학과) ;
  • 허린수 (경북대학교 농과대학 수의학과)
  • Received : 1987.01.23
  • Published : 1987.04.30

Abstract

Determination of cholinesterase activity is a routine practice in many laboratories to detect the influence of cholinesterase inhibiting drugs such as organophosphate and carbamate insecticides. Among many different methods to determine the cholinesterase activity, the present method was the most recent, simple and accurate one for routine test in clinics. The results obtained in sera of human and the different species of animals by means of the present method were as follows: $5.76{\pm}1.12U/ml$ in human, $3.37{\pm}0.83U/ml$ in german shepherd, $0.61{\pm}0.18U/ml$ in rat, $14.91{\pm}3.10U/ml$ in mouse, $1.55{\pm}0.51U/ml$ in chicken, $0.28{\pm}0.11U/ml$ in slaughtered cattle and $0.50{\pm}0.10U/ml$ in slaughtered pig.

Keywords