The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 22 Issue 4
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- Pages.473-483
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- 1987
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- 0253-3162(pISSN)
Study of Measles, Mumps and Rubella Antibodies by Enzyme Immunoassay in Infants and Children in Korea
효소 면역측정법에 의한 한국 영아 소아의 홍역 볼거리 및 풍진 항체에 관한 연구
- Park, Hae-Kyung (Department of Microbiology, College Medicine, Ewha Womans University) ;
- Kee, Bock-Keun (Department of Pediatrics, School of Medicine, Won Kwang University)
- Published : 1987.12.31
Abstract
Present study was undertaken to find when is right time for vaccination against Measles, Mumps and Rubella and what is the seropositive conversion rate after those vacinations. For this purpose, sera from 106 infants and children adimitted in Prediatric Department of Won Kwang University Hospital, Iri, Chonbuk, Korea were divided into 3 groups, such as (1) Vaccination group with definite information when it was given, (2) Unknown group whether vaccination was given or not, (3) Not vaccinated group. They were tested of IgG and IgM antibodies against Measles, Mumps and Rubella using Enzyme Immunoassay method and the following results were obtained. 1. Infants below 6 month of age showed to have IgG antibodies which seemed to have been transferred from mother in 87.8%(29/33) for Measles, 78.8%(26/33) for Mumps and 39.4%(13/13) for Rubella. And they showed IgM antibodies which are thought to have been produced by recent infection in 24.2%(8/33) for Measles, 48.5%(16/33) for Mumps and 9.1%(3/33) for Rubella. 2. Positivity of antibody IgG against Rubella was observed remarkably lower than it is against Measles and Mumps being only 39.4%(13/33) in