Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)
- Volume 13 Issue 1
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- Pages.1-6
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- 1987
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- 1226-2587(pISSN)
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- 2288-9507(eISSN)
A STUDY OF THE PHOTOTOXICITY OF ORANGE FLOWER ABSOLUTE
- Yang, Hai-Joo (Pacific R & D Center) ;
- Lee, Neung-An (Pacific R & D Center)
- Published : 1987.10.01
Abstract
We have confirmed the phototoxicity of orange flower absolute, studied the phototoxic ingredient and developed a method to eliminate it. To confirm the phototoxicity, we tested French orange flower absolute, Moroccan absolute and Egyptian absolute with Hartley strain guinea Pig under UV irradiation ranging from 320400 nm supplied with fluorescent lamps. Using a combination of isolation techniques including HPLC and IR, we were able to confirm that the phototoxic agent was bergapten. The development of a non-phototoxic orange flower absolute using ion exchange chromatography is described.
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