Journal of Pharmaceutical Investigation
- 제17권2호
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- Pages.95-98
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- 1987
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
프로베네시드와 탄산리튬의 약물상호작용
Drug Interaction of Probenecid and Lithium Carbonate
- Lee, Jin-Hwan (College of Pharmacy, Chosun University) ;
- Lee, Chong-Ki (College of Pharmacy, Chosun University)
- 발행 : 1987.06.20
초록
The drug interaction between probenecid and lithium carbonate was studied pharmacokinetically in rabbits. The blood level and the area under the concentration curve (AUC) of lithium carbonate administered orally were elevated by coadministration of probenecid. Probenecid inhibited the urinary excretion of lithium carbonate in rabbits. Biological half-life and
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