대한미생물학회지 (The Journal of the Korean Society for Microbiology)
- 제21권3호
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- Pages.375-380
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- 1986
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- 0253-3162(pISSN)
녹농균에 대한 Aminoglycoside계와 Cephalosporin계의 병합작용
Combined action of Aminoglycoside and Cephalosporin Against Pseudomonas aeruginosa
- Oh, Jong-Suk (Department of Microbiology, Chonnam National University Medical School) ;
- Ahn, Tai-Hew (Department of Microbiology, Chonnam National University Medical School)
- 발행 : 1986.09.30
초록
Thirty-one strains of Pseudomonas aeruginosa were submitted to the synergistic activity test of amikacin(AK) and gentamicin(GM) combined with moxalactam(MX), ceftizoxime(CTZ) or cefoperazone(CFZ). The minimal inhibitory concentrations(MICs) of each drug and drugs combined in various ratios were measured by checkerboard dilution method. The synergism was determined through analysing the MIC distribution curve on isobologram and calculating the fractional inhibitory concentration index(FICI). MICs of GM, AK, MX, CFZ and CTZ against the 31 tested strains were distributed from