Journal of Ginseng Research
- 제10권1호
- /
- Pages.108-113
- /
- 1986
- /
- 1226-8453(pISSN)
- /
- 2093-4947(eISSN)
인삼 사포닌의 동물(쥐) 체내흡수에 관한 연구
Absorption of Ginseng Saponin in Rats
- Ju, Chung-No (Department of Biochemistry, College of Science Yonsei University) ;
- Lee, Hui-Bong (Department of Biochemistry, College of Natural Science Kangwon University) ;
- Kim, Jae-Won (Department of Biochemistry, College of Science Yonsei University)
- 발행 : 1986.06.01
초록
인삼(Panax ginseng C. A. Meyer)뿌리 절편을 효소원으로 사용하여
Ginseng saponin absorbed in rat blood and liver were analyzed by High Performance Liquid Chromatography. The amount of saponin was estimated from peak area of the corresponding fraction and the specific radioactivity was then calculated, The radioactivity of the methanol-water extract of blood serum and livers of ginseng saponin administered rats decreased rapidly during the first four hours after the saponin administration. However, the radioactivity disappearance rate was relatively slow when the radioactivity was below a certain level. It seemed that the glycosides of panax ginseng were absorbed partly in the undissociated form and the saponin level of the liver might be maintained at 10-6% - 10-5% for a considerable period of time in ginseng administered rats.
키워드