Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Synthesis of 2-Acylaminobenzothiazole and Benzothiazolylurea Derivatives and Their Biological Activities

2-Acylaminobenzothiazole 및 Benzothiazolylurea 유도체(誘導體)의 합성(合成)과 생리활성(生理活性)에 관한 연구(硏究)

  • Lee, Chun-Soo (Department of Chemical Engineering, College of Engineering, Keimyung University) ;
  • Lee, Jung-Yong (Department of Chemical Engineering, College of Engineering, Keimyung University) ;
  • Hong, Jong-Uck (Department of Agricultural Chemistry, College of Agriculture, Kyung pook National Univeristy)
  • 이천수 (계명대학교 공과대학 화학공학과) ;
  • 이정용 (계명대학교 공과대학 화학공학과) ;
  • 홍종욱 (경북대학교 농과대학 농화학과)
  • Published : 1986.12.10
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Abstract

2-Acylaminobenzothiazole derivatives were synthesized from 2-aminobenzothiazole and acylchloride. Benzothiazolylurea derivatives were syntesized from 2-minobenzothiazole and phenylisocyanate. The products were identified by UV, IR, $^1H-NMR$, $^{13}C-NMR$ spectra with 2-acetamidobenzothiazole(I), 2-propionamidobenzothiazole(II), 2-butamidobenzothiazole(III), 2-benzamidobenzothiazole(IV). The compounds were tested for their phytotoxicity on the germination and seedling growth of rice, radish and green pea plants, It was found that treatment of 500ppm concentration each of 2-acetamidobentothiazole, 2-propionarmidobenzothiazole and 2-butamidobenzothiazole strongly inhibited of seedling growth of the radish and green pea.

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