Pharmacological Studies on Prunellae Herba and Thesii Herba (I) -On Antiinflammatory Activity-

한국산(韓國産) 하고초류(夏枯草類)의 약물학적(藥物學的) 연구(硏究)(I) -소염작용(消炎作用)에 대하여-

  • Ko, In-Ja (College of Pharmacy, Sung Kyun Kwan University) ;
  • Yoo, Seung-Jo (College of Pharmacy, Sung Kyun Kwan University) ;
  • Lee, Eun-Bang (Natural Products Research Institute, Seoul National University)
  • Published : 1986.09.30

Abstract

The whole plants of Prunella vulgaris (Labiatae) and Thesium chinense (Santalaceae) are used as Hakocho(夏枯草) in the market in Korea. In oriental medicine, these herb drugs are prescribed as a diuretic or antiinflammatory drugs. In order to investigate the efficacy of the plants, the extracts were bioassayed for antiinflammatory action. The water extracts of Prunella Herba and Thesii Herba showed remarkable anti-carrageenin effect and significant inhibition of the swellings in adjuvant arthritis in rats. However, the extracts did not show any inhibition of leucocyte emigration in CMC pouch in rats.

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