생약학회지 (Korean Journal of Pharmacognosy)
- 제16권2호
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- Pages.99-104
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- 1985
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Iridoid Compounds가 RNA 및 Protein 생합성에 미치는 영향
Effects of Iridoid Compounds on RNA and Protein Biosyntheses in Sarcoma 180 cells
초록
To investigate a possible biological activity of iridoid glucosides, six compounds, aucubin, catalpol, gardenoside, geniposide, rehmannioside and swertiamarin, were studied in relation with their potential influences in RNA and protein biosyntheses in murine tumor cell, sarcoma 180, in vitro. Protein biosynthesis was slightly inhibited by aucubin, gardenoside and swertiamarin. Degree of inhibition of RNA biosynthesis by those iridoid appeared to be more sensitive than that of protein biosynthesis. When aucubin was pretreated with