The Korean Journal of Physiology
- 제19권2호
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- Pages.127-137
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- 1985
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- 0300-4015(pISSN)
Rehmanniae Radix에 의한 가토 동방결절 및 유두근의 활동전압의 변동
Effects of Ethanol Extract of Rehmanniae Radix(RREE) on Resting and Action Potential of Rabbit Sinoatrial Node and Papillary Muscle
- Hwang, Bo-Sang (Department of Physiology, College of Medicine, Hanyang University) ;
- Koh, Sang-Don (Department of Physiology, College of Medicine, Hanyang University) ;
- Shin, Hong-Kee (Department of Physiology, College of Medicine, Hanyang University) ;
- Kim, Kee-Soon (Department of Physiology, College of Medicine, Hanyang University)
- 발행 : 1985.12.30
초록
The present study was undertaken in order to investigate effect of ethanol extract of Rehmanniae radix(RREE) on electrophysiology of sinus node and papillary muscle. Rehmanniae radix is a herbal medicine which has been known to have diuretic, antipyretic, hemopoietic and cardiotonic effects. Action potentials were recorded by means of glass capillary microelectrode(technique) in rabbit sinoatrial nodal cells and papillary muscle cells which were superperfused with either tyrode solution or tyrode solutions containing different amount of RREE. The results obtained were as follows ; 1) In both central and peripheral nodal cells maximum diastolic potential (MDP) and amplitude of action potential (APA) were not affected by RREE. 2) Action potential duration as expressed
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