대한핵의학회지 (The Korean Journal of Nuclear Medicine)
- 제18권1호
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- Pages.19-24
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- 1984
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- 1225-6714(pISSN)
갑상선질환(甲狀腺疾患)에서의 자가항체(自家抗體)의 임상적(臨床的) 의의(意義)
Clinical Significance of Autoantibodies in Some Thyroid Disorders
- 최성규 (서울고려병원 내과) ;
- 한상호 (서울고려병원 내과) ;
- 김영주 (서울고려병원 내과) ;
- 송준호 (서울고려병원 내과) ;
- 이만호 (서울고려병원 내과) ;
- 정을순 (서울고려병원 내과) ;
- 이상종 (서울고려병원 내과)
- Choi, Sung-Kyu (Dept. of Internal Medicine, Korea General Hospital) ;
- Han, Sang-Ho (Dept. of Internal Medicine, Korea General Hospital) ;
- Kim, Young-Ju (Dept. of Internal Medicine, Korea General Hospital) ;
- Song, Jun-Ho (Dept. of Internal Medicine, Korea General Hospital) ;
- Lee, Man-Ho (Dept. of Internal Medicine, Korea General Hospital) ;
- Chung, Eul-Sun (Dept. of Internal Medicine, Korea General Hospital) ;
- Lee, Sang-Jong (Dept. of Internal Medicine, Korea General Hospital)
- 발행 : 1984.11.22
초록
Clinical measurement of thyroid autoantibodies in sera of some thyroid disorders have been widely applied since about twenty years ago. We investigated the incidence and titers of both anti microsomal and antithyroglobulin antibodies in forty eight cases with controls and one hundred and thirty three patients with some form of thyroid disorders. The results were as follows; 1) In controls, antimicrosomal antibodies were positive in 2% but anti thyroglobulin antibodies were all negative. 2) In a series of one hundred and thirty three patients with thyroid disease, anti microsomal antibodies were positive in 44% but antithyroglobulin antibodies were positive in only 15%. 3) The rate disclosing the positive results of antimicrosomal antibodies were 71 % in Hashmoto's disease, 60% in Graves' disease, and 38% in primary hypothroidism, respectively. On the other hand, the positive results of antithyroglobulin antibodies showed 21 % in Graves' disease, 19% in primary hypothyroidism, and 18% in Hashmoto's disease, respectively. Though there were relatively high rate of both antimicrosomal and anti thyroglobulin antibodies in patients with nodular goiter, they were only seven cases in our series. 4) The rate with the extremely high titers of antimicrosomal and antithyroglobulin antibodies
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