Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis of Nucleophilic Adducts of Thiols (Ⅴ). Addition of Thioglycolic Acid to $\omega,\;\omega$-Diacetylstyrene Derivatives

  • Huh, Tae-Sung (Department of Chemistry, Song Sim College for Women) ;
  • Han, Hae-Sook (Department of Chemistry, Song Sim College for Women) ;
  • Han, In-Sup (Department of Chemistry, Kangweon National University) ;
  • Kim, Tae-Rin (Department of Chemistry, Korea University)
  • Published : 1984.02.20
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Abstract

The addition reactions of thioglycolic acid to ${\omega}$, ${\omega}$-diacetylstyrene derivatives were investigated. ${\omega}$, ${\omega}$-Diacetylstyrene derivatives easily undergo addition reactions with thioglycolic acid to form s-(2, 2-diacetyl-1-phenylethyl)-thiogycolic acid, s-[2,2-diacetyl-1-(methyl) phenylethyl]-thioglycolic acid, s-[2,2-diacetyl-1-(p-methoxy) phenylethyl]-thioglycolic acid and s-[2,2-diacetyl-1-(p-chloro) phenylethyl]-thioglycolic acid, respectively. The structures of these compounds were identified by neutralization equivalent, UV, IR, and NMR spectral data.

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