YAKHAK HOEJI (약학회지)
- Volume 28 Issue 2
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- Pages.89-95
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- 1984
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Screening of Microorganisms Having Inhibitory Activity against $\beta$ -lactamase
$\beta$ -Lactamase 저해능이 있는 방선균의 선별
Abstract
Microorganisms having beta-latamase inhibitory activity were selected from soil samples collected from 63 spots throughout the country. Screening procedures consist of two steps. Those are growth inhibition test of penicillinase-producing Staphylococcus aureus by double-layered agar plate containing penicillin G as a substrate, and that of penicillin sensitive Staphylococcus aureus ATCC 6538 in the similiar condition including penicillinase. Finally, a strain was selected from a soil sample of Pa-ju, Kyeong-gi Do. This strain was classified as a Streptomyces sp. by ISP(International Streptomycete Project) and Bergey's manual.
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