Studies on Antibiotic Producers of Korean Soil Microbes(I) -Isolation and Antibiotic Activity of Streptomyces Strain DMC-72-

한국(韓國) 토양균(土壤菌)중 항생물질(抗生物質) 생성균(生成菌)에 관한 연구(硏究)(제1보)(第1報) -스트렙토마이세스속(屬) 균주(菌株) DMC-72호(號)의 분리(分離) 및 항균작용(抗菌作用)-

To find antimicrobial strains of the soil microorganisms in Korea, they were isolated from the soil samples of different locations and screened for antibiotic activity against several standard microbes. An isolate among them had an antibacterial activity against gram-positive bacteria. The examination of its morphological and biochemical characteristics according to the International Streptomyces Project methods showed that it belongs to the genus Streptomyces. The strain was named DMC-72. The strain appears to be a new strain when it was compared with the species within the genus which have been so far reported. The antibiotic metabolite of the strain was produced in submerged culture method. It was found to be a quinone compound and was named soulomycin. This strain was also found to produce an ${\alpha}-amylase$ inhibitor in the submerged culture.