The Journal of the Korean Society for Microbiology (대한미생물학회지)

The Korea Society for Microbiology (대한미생물학회)
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Suppression of the Development of Delayed-Type Hypersnsitivity to Sheep Erythrocytes by Serum from BCG-Infected Mice

BCG 감염(感染)마우스 혈청(血淸)에 의(依)한 지연성(遲延性) 과민반응(過敏反應) 억제(抑制)

  • Lee, Hern-Ku (Department of Microbiology and Immunology, Jeonbug National University, Medical School) ;
  • Kim, Tae-Gon (Department of Microbiology and Immunology, Jeonbug National University, Medical School) ;
  • Ha, Tai-You (Department of Microbiology and Immunology, Jeonbug National University, Medical School)
  • 이헌구 (전북대학교 의과대학 미생물학교실) ;
  • 김태곤 (전북대학교 의과대학 미생물학교실) ;
  • 하대유 (전북대학교 의과대학 미생물학교실)
  • Published : 1983.12.31
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Abstract

The immunosuppressive effect of serum from mice heavily infected with BCG(BCG-serum) was evaluated. The delayed-type hypersensitivity reaction to sheep erythrocytes was depressed when BCG-serum was administered both systemically and locally at the same time of challenge. This study shows that serum of animal infected with mycobacteria contains a factor responsible for immunosuppression and factor may be important in understanding the mechanisms of allergy in mycobacteria] infections.

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