대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)
- 제4권1호
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- Pages.9-14
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- 1983
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- 1229-0807(pISSN)
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- 2288-9396(eISSN)
Computer Simulation of Glucose-insulin Kinetics During Intravenous Glucose Tolerance Test
초록
A new quantitative method was developed for separation of three interactive physiological factors (hepatic glucose balance, peripheral tissue's insulin resistivity, and insulin secretion rate) influencing glucose intolerance in diabetic mellitus using an equivalent circuit model and the intravenous glucose tolerance test (IVGTT) in six dogs and twenty two humans. The results show that the estimated model parameters of the above three factors are useful for evaluating different glucose-insulin kinetics in normal and diabetic subjects.
키워드