YAKHAK HOEJI (약학회지)
- Volume 27 Issue 4
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- Pages.321-329
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- 1983
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Mechanism of the Monoamine Oxidase Inhibition
Monoamine Oxidase의 억제 기구
Abstract
The review characterized active site(s) of MAO with respect to metal ions, hydrophobic and polar region, sulfhydryl group and flavin moiety. The mechanism of inhibition was dealt with three representative types of inhibitors; phenylcyclopropylamines, acetylenic amines, and hydrazines. Multiple forms of MAO was shortly described in relation to their selective inhibition. 84 reference were cited.
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