YAKHAK HOEJI (약학회지)
- Volume 27 Issue 4
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- Pages.263-270
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- 1983
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Pharmacological Studies on Butanol Fraction of Puerariae Radix
갈근 Butanol Fraction의 약리 작용에 관한 연구
Abstract
Effective BuOH fraction was extracted from Puerariae radix (Pueraria thunbergiana), and several pharmacological activities were examined. From several pharmacological examinations, it was found that BuOH fraction has an antipyretic activity against typhoid vaccine pyrexia in rabbit, a papaverine-like antispasmodic activity on isolated ileum and jejunum of rat, an analgesic effects on mice treated by 0.7% HAc, and an anti-inflammatory activity of carrageenin edema in rat. It was found that BuOH fraction has detoxication effects on acute and subacute toxic rat induced by alcohol in consequence of biochemical tests of serum. Therefore it was considered that BuOH fraction has preventive and therapeutic effects in alcohol intoxication.
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