Archives of Pharmacal Research
- 제6권1호
- /
- Pages.45-53
- /
- 1983
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Halolactonization reaction using N-haloimides
- Cook, Chae-Ho (College of Pharmacy, Seoul National University) ;
- Cho, Youn-Sang (College of Pharmacy, Seoul National University) ;
- Jew, Sang-sup (College of Pharmacy, Seoul National University) ;
- Suh, Young-Guh (College of Pharmacy, Seoul National University) ;
- Kang, Eung-Ku (College of Pharmacy, Seoul National University)
- 발행 : 1983.06.01
초록
Novel halactolactonizations using NBS (2), NIS(3), and NSP(4) in dry DMF were found to be the most reasonable and efficient procedures. The participation of X as the cylization initiator could be clarly rationalized by experimental results and the regioselectivities of formed halolactones were reasonably elucidated by weakly bridged carbonium ion intermediate.
키워드