Journal of Ginseng Research
- Volume 7 Issue 1
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- Pages.80-87
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- 1983
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- 1226-8453(pISSN)
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- 2093-4947(eISSN)
Effects of Ginseng Saponin on the Regu lately Properties of Malate Dehydrogenase from Pigeon Breast Muscle
인삼사포닌이 비둘기 가슴근육으로부터 분리된 Malate Dehydrogenase의 조절기능에 미치는 영향
- Kim, Du-Ha (Korea Ginseng & Tobacco Research Institute) ;
- Sin, Mun-Hui (Korea Ginseng & Tobacco Research Institute) ;
- Hong, Sun-Geun (Korea Ginseng & Tobacco Research Institute)
- Published : 1983.06.01
Abstract
In an endeavour to elucidate effects of ginseng on some characteristics of enzymes, malate dehydrogenase (EC 1.1.1.37) was chosen as a model enzyme and effects of ginseng saponin on the enzyme such as optimum pH, product inhibition, optimum temperature and the activity was investigated. The product inhibition by NADH-a reaction product of the enzyme-was increased 33% by 0.3% ginseng saponin. And the optimum pH of the enzyme was 8.3 but in the presence of 0.3% ginseng saponin it increased to 8.5. The enzyme activity and the optimum temperature was not affected by ginseng saponin in the concentration of 1.0% and 0.3%, respectively. In this work, the possibility of contribution of ginseng saponin to the adaptogen activity is suggested; Potentiation of the regulatory activity of an enzyme may contribute to the normalization of the physiological state and consequently may increase the nonspecific resistance of an organism.
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