YAKHAK HOEJI (약학회지)
- Volume 26 Issue 3
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- Pages.181-184
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- 1982
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Synthesis of Iron and Copper Complexes of 2-Formylpyridine Thiosemicarbazone Derivatives, Potential Antitumor Agents
실험 항암제 2-Formylpyridine Thiosemicarbazone유도체의 철 및 동착물의 합성
Abstract
The iron and copper chelates of 4-dimethylamino-2-formylpyridine thiosemicarbazone, one of the amine substituted derivatives at 4-C of 2-formylpyridine thiosemicarbazones which are known as the more improved potential antitumor agents, have been synthesized to make them more effective than the ligand (denoted as HL) itself. Their ligand-to-metal ratios were 2:1 and 1:1 for the iron and copper chelates, and the data along with those of elemental analysis and IR spectroscopy showed that. the compositions are [
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