Archives of Pharmacal Research
- Volume 5 Issue 2
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- Pages.93-96
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- 1982
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
A novel bromolactonization reaction using racemic 2-bromo-5-isobutyl-5-methylhydantoin
- Cho, Youn-Sang (College of Pharmacy, Seoul National University) ;
- Jew, Sang-Sup (College of Pharmacy, Seoul National University) ;
- Chung, You-sup (College of Pharmacy, Seoul National University)
- Published : 1982.12.01
Abstract
By using recemic 3-bromo-5-isobutyl-5-methylhydantoin (3a') in dry N, N-dimethylformamide which is a model reagent for asymmetric bromolactonization, bromolactonization of a series of olefinic acids was carried out to furnish corresponding bromolactones in moderate yields.
Keywords
- Bromolactonization;
- 3-Bromo-5-isobu-tyl-5-methylhydantion;
- N;
- N-Dimethylformamide;
- Bromolactone;
- A model reagent for asymmetric bromolactionization