Journal of Pharmaceutical Investigation
- 제12권3호
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- Pages.55-63
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- 1982
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Sulpiride의 Polymorphism 및 그 약제학적(藥劑學的) 연구(硏究) (제3보)(第三報) -Polymorph에 따른 용출속도(溶出速度)-
Polymorphism of Sulpiride and Its Pharmaceutical Applications ( III ) -Dissolution Kinetics of Sulpiride Polymorphs-
- Lee, Min-Hwa (College of Pharmacy, Seoul National University) ;
- Kim, Kil-Soo (College of Pharmacy, Seoul National University)
- 발행 : 1982.09.20
초록
The dissolution kinetics for polymorphs of sulpiride, the effect of polyethylene glycol 4000 on the dissolution kinetics of sulpiride polymorphs and the dissolution rate difference between the tablets of polymorph form I and form II were investigated. The results could be summerized as followings: 1. The dissolution rates of two polymorphs of sulpiride were significantly different and the thermodynamic parameters calculated from dissolution kinetics were as follows; transition temperature
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