생약학회지 (Korean Journal of Pharmacognosy)

  • 제13권1호
  • /
  • Pages.14-19
  • /
  • 1982
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

한국산 생약의 약리작용 및 독성연구 (제2보) -급성 독성 및 골수세포의 DNA생합성에 미치는 영향-

Toxicological Evaluation of Medicinal Plants Used for Herbal Drugs (II) -Acute Toxicity and Effects on DNA Biosynthesis in Bone Marrow Cells and Hemoglobin Content in Blood-

  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
  • Kim, Young-Soo (Natural Products Research Institute, Seoul National University) ;
  • Han, Byung-Hoon (Natural Products Research Institute, Seoul National University)
  • 발행 : 1982.03.30
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초록

Potential toxicity of 15 medicinal plants used for herbal drugs, which were also described as being tonic for hematopoietic system or being toxic for the system in a oriental book 'Dong Ee Bo Gam', were evaluated in mice. Six plants among 15 plants tested appeared to exhibit acute toxicity along with bone marrow depression or with abnormally enhancing the $^3H-thymidine$ incorporation into DNA biosynthesis in bone marrow cells. Six plants were Paeonia albiflora, Pharbitis nil, Cemphalia lapidescens, Scutellaria baicalensis, Akebia quinata and Glycyrriza uralensis.

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