Studies on the Efficacy of the Combined Preparation of Crude Drugs (VI) -Effect of 'Saengkankunbi-Tang' on Activities of the Liver Enzyme, Protein Contents and the Excretory Action of Bile Juice in the Serum of $CCl_4$-intoxicated Rabbits

생약복합제제(生藥複合製劑)의 약효연구(藥效硏究) 제6보(第6報) -생간건비탕(生肝健脾湯)의 혈청중(血淸中) 효소활성도(酵素活性度), 성분함량(成分含量) 및 이담효과(利膽效果)에 대(對)한 작용(作用)-

  • Published : 1982.03.30

Abstract

In order to investigate the pharmacological action of the combined preparation of crude drugs, 'Saengkankunbi-Tang' were studied. These studies were conducted in an attempt to investigate the effect of 'Saengkankunbi-Tang' on activities of the liver enzyme, protein contents and the excretory action of bile juice in the serum of $CCl_4-intoxicated$ rabbits. The results of this investigate were summarized as follows; GOT, GPT activities and total cholesterol contents in the serum of rabbits induced by $CCl_4$ were shown to the remarkable decrease with the passage of the time in the oral administration of the sample. Albumin contents in the serum of rabbits induce by $CCl_4$ were noted to the significant increase with the passage of the time. Serum total protein contents were noted to the significant increase only the 4th and 6th day. BSP accumulation contents in the serum of rabbits induced by $CCl_4$ showed the remarkable decrease with the passage of the time.

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