The Journal of the Korean Society for Microbiology (대한미생물학회지)
- Volume 16 Issue 1
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- Pages.83-89
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- 1981
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- 0253-3162(pISSN)
Propagation and Attenuation of Japanese Encephalitis Virus in Tissue Culture Cells
조직배양세포에서의 일본뇌염virus 증식에 관한 연구
- Lee, Ho-Wang (Department of Microbiology, College of Medicine and Institute for Viral Diseases, Korea University) ;
- Moon, Seok-Bae (Department of Microbiology, College of Medicine and Institute for Viral Diseases, Korea University)
- Published : 1981.12.31
Abstract
Japanese encephalitis has been prevalent for long time in the Far East and many patients have been reported in both South East and Mid-West Asia recently. Recently, vaccine was used in prevention of this viral disease of man which was derived from formalin inactivated virus inoculated into mouse brain, but live attenuated active vaccine for human is not developed yet. Author inoculated Japanese encephalitis virus into several cell culture strains for development of live attenuated encephalitis virus strain and the results were as follows: 1. Japanese encephalitis virus was inactivated rapidly in cell free medium at
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