약학회지 (YAKHAK HOEJI)
- 제25권1호
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- Pages.1-7
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- 1981
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
생약중의 감초에 관한 연구(I) HPLC에 의한 Glycyrrhizin 및 Glycyrrhetinic acid의 정량
Studies on Licorice in Drug Preparations(I) Determination of Glycyrrhizin and Glycyrrhetinic acid by HPLC.
초록
Glycyrrhizin (GA) content in licorice was determined by a couple of methods using HPLC, respectively. In Method(I), GA content itself was determined from the licorice aqueous extract, while in Method (II) glycyrrhetinic acid (GHeA ; the aglicone of GA) content corresponding to the quantity of GA was measured from the chloroform extract of the hydrolyzed product of licorice aqueous extract. A reverse phase column Hibar Lichrosorb RP-18 (E. Merck) was used as the stationary phase. As the mobile phase MeOH:
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