Archives of Pharmacal Research
- Volume 4 Issue 2
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- Pages.133-135
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- 1981
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
3-bromo-5,5-dimethylhydantoin induced ring closure (I)
- Cook, Chae-Ho (College of Pharmacy, Seoul National University) ;
- Chung, You-Sup (College of Pharmacy, Seoul National University)
- Published : 1981.12.01
Abstract
Reaction of unsaturated acids with 3-bromo-5, 5-dimenthylhydantoin in dry DMF at room temperature gives bromolactones in 58-91 % yields.
Keywords
- Bromolactonization;
- 3-Bromo-5,5-dimethylhydantion;
- N,N-Dimethylformamdie;
- ${\gamma}$-Bromo-$\beta$-lactone