Archives of Pharmacal Research
- 제4권1호
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- Pages.1-8
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- 1981
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Determination of the optical isomers of ethambutol (myambutol) and 2-amino-1-butanol by gas-liquid chromatography
- Kim, Ye-Sook (College of Pharmacy, Seoul National University) ;
- Youm, Jeong-Rok (College of Pharmacy, Seoul National University) ;
- Park, Man-Ki (College of Pharmacy, Seoul National University) ;
- Paik, Nam-Ho (College of Pharmacy, Seoul National University)
- 발행 : 1981.06.01
초록
Our need for a convenient method of analytical estimation of the precise optical purity of d-2 aminobutanol (d-2AB) and d-ethambutol has prompted us to examine in detail the preparation and G. L. C. separation of the N-TFA-L-prolyl derivatives of their optical isomers (d-and l-2AB, d-, meso-and l-ethambutol). Silicon OV-1 columns were used for the G. L. C. separation.