Studies on the Quality Control Method of Crude Drug Preparations (I) -Studies on the Quality Control by the TLC Profiles Analysis of ‘Samyo-Tang’-

생약복합제제(生藥複合製劑)의 품질관리(品質管理)에 관(關)한 연구(硏究)(제1보)(第1報) -TLC Scanner에 의(依)한 삼요탕(三拗湯)의 품질관리(品質管理)-

  • Published : 1981.09.30

Abstract

In our country, in order to cure diseases, a large number of crude drug preparations has been available. Nevertheless, the development of crude drug preparations have been inhibited, because the quality control is not completed so far. Therefore, we have eontinued on studing the quality control method by Zig-zag TLC. profile analysis. The water extract of 'Samyo-Tang' and componental crude drug (Glycyrrhizae Radix, Ephedrae Herba, Armenicae Semen) were developed on Silica gel $60F_{254}\;plate\;(E.\;Merck)$ useing elution solvent. The developed plate were examined useing Dual Wavelength Zig-zag Scanner (Shimadzu). According to the results of the experiment, it could be summarized as follow: 1) Original patterns of TLC profiles of 'Samyo-Tang' componental crude drug and mixing two crude drugs of 'Samyo-Tang' were observed. 2) Original patterns TLC profile of each extract after spraying with 2% ninhydrine were observed. 3) In the extract of addition and subtraction of Ephedrae Herba, peak area of Rf 0.48 and Rf 0.60 were varied quantitatively.

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