The Korean Journal of Physiology
- 제15권2호
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- Pages.83-89
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- 1981
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- 0300-4015(pISSN)
식후 정상 한국인의 혈장 gastrin 농도
Plasma Gastrin Concentration after a Carbohydrate Meal and a Protein Meal in Normal Human Subjects
- 김명석 (가톨릭대학 의학부 생리학교실) ;
- 박형진 (가톨릭대학 의학부 생리학교실) ;
-
조양혁
(가톨릭대학 의학부 생리학교실) ;
- 권경옥 (가톨릭대학 의학부 생리학교실) ;
- 이윤렬 (가톨릭대학 의학부 생리학교실)
- Kim, Myung-Suk (Department of Physiology, Catholic Medical College) ;
- Park, Hyoung-Jin (Department of Physiology, Catholic Medical College) ;
-
Jo, Yang-Hyeok
(Department of Physiology, Catholic Medical College) ;
- Kwon, Kyoung-Ok (Department of Physiology, Catholic Medical College) ;
- Lee, Yoon-Lyeur (Department of Physiology, Catholic Medical College)
- 발행 : 1981.12.31
초록
한국 정상 성인에서 탄수화물 음식물(쌀밥)과 단백질 음식물(햄버거)의 섭취가 혈장 gastrin 농도에 미치는 영향을 알아 보기 위하여 다음과 같은 실험을 실시하였다. 평균 연령이 28세(
This study was conducted to investigate the effect of the ingestion of rice and hamburger meals upon the plasma gastrin concentration in normal human subjects in Korea. Eight normal human subjects including male and female with the mean age of 28 years (range: 20-40 years) were studied. After an overnight(about 15 hrs) fast each subject ingested a rice meal and a hamburger meal on different days. The rice meal consisted of 250 g boiled rice, 50 g vegetables and 200 ml barley tea, corresponding to 6.8 g protein, 0.5 g fat and 81g carbohydrate and the hamburger meal consisted of 200 g hamburger, 50 g vegetables ana 200 ml milk, corresponding to 43 g protein, 43 g fat and 9 g carbohydrate. The venous blood samples were drawn before and after the ingestion of the test meal at the following times: -30, 0, 15, 30, 45, 60, 90, and 120 min, for measurement of gastrin by radioimmunoassay. The following results were obtained : 1) Plasma gastrin concentration in response to the ingestion of the rice or the hamburger meal increased significantly compared with the concentration in fasting state. 2) The increase of the plasma gastrin concentration after the hamburger meal was significantly higher than that after the rice meal. 3) There was a significant linear correlation between the postprandial peak plasma gastrin concentration after the rice meal and the concentration after the hamburger meal in each subject. It is inferred from the above results that a carbohydrate meal as well as a protein meal has a stimulatory effect on gastrin release in normal human subjects.
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