EXPERIMENTAL STUDY ON THE EFFECT OF FORMOCRESOL TO THE PULP TISSUE

Formocresol이 치수조직(齒髓組織)에 미치는 영향(影響)에 관(關)한 실험적(實驗的) 연구(硏究)

The purpose of this study was to evaluate the pulpal response against calcium hydroxide and zinc oxide containing various concentration of formocresol (0.1, 0.5, 1, 5, 10, 20 and 30%). The experiment was performed on dog's teeth (75 teeth from 5 dogs: Table 1.) and the teeth were routinly treated in laboratory procedures. Followings are the results obtained through microscopical examination. 1. In zinc oxide group, intlammatory reaction was severe in low concentrated formocresol and the (higher the concentration of formocresol the milder the inflammatory reaction was more evident. 2. In zinc oxide group, inflammatory change was milder at 3 weeks than 1 week, and proliferation of young connective tissue was seen at 3 weeks. 3. In calcium hydroxide group, inflammatory change in relation to the concentration of formocresol was not noticeable. 4. In calcium hydroxide group, repair process with decreased inflammatory reaction and fibrosis, and dentin bridge like layer was found at 3 weeks.