Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Screening of Korean medicinal plants for antitumor activity

  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
  • Woo, Won-Sick (Natural Products Research Institute, Seoul National University)
  • Published : 1980.12.01
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Abstract

Potential antinumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tomor model. Survival studies by measuring life span indicated that Morus alba (Moraceae), Verbascum phlomoides (Scrophulariaceae), Curcuma longa (Zingbieraceae), Torilis japonica (Umbelliferae), Bupleurum falcatum (Umbelliferae) and Codonopsis pilosula (Campanulaceae) exhibited significant antitumor activity with the dose-schedule employed in the experiment. Methanol (70%) extracts of Platycodon gradiflorum (Campanulaceae), Bupleurum longeradiatum (Umbelliferae) and Asiasarum sieboldii (Aristolochiaceae) showed rather potent toxicity.

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