Journal of Chest Surgery
- Volume 12 Issue 4
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- Pages.395-402
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- 1979
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- 2765-1606(pISSN)
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- 2765-1614(eISSN)
An Experimental Study of Lactic Acidosis and Potassium Transfer in the Dog
락트산 산증과 칼륨이동에 관한 실험적 연구
Abstract
Intracellular pH was determined by distribution of 5.5-dimethyl-2,4-oxazolidlnedione [DMO]in the skeletal muscle of dogs before and after lactic acidosis induced by intravenous infusion of lactic acid solution. After infusion of lactic acid solution arterial pH decreased from 7.40 to around 7.12 [P<0.001]and metabolic acidosis was induced. However, dose-pH change response was not proportional as in the case of hydrochloric acid infusion. During lactic acidosis, intracellular pH changed very little except when venous blood
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