Journal of Pharmaceutical Investigation

The Korean Society of Pharmaceutical Sciences and Technology (한국약제학회)
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The Effect of Lactose and Corn'starch on Compressed Dosage Form Design of Furazolidone

Lactose 및 Corn'starch가 Furazolidone의 압축성형(壓縮成型)에 미치는 영향(影響)

  • Yeom, Yoon-Hee (College of Pharmacy, Sookmyung Women's University) ;
  • Yong, Jae-Ick (College of Pharmacy, Sookmyung Women's University)
  • 염윤희 (숙명여자대학교 약학대학) ;
  • 용재익 (숙명여자대학교 약학대학)
  • Published : 1979.03.20
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Abstract

Furazolidone tablets were made of lactose and corn'starch as adjuvants by compression method. Six formulations were used with variation of lactose and starch contents. Dissolution, disintegration, content unifomity, hardness, and weight variation were examined for furazolidone tablets. Furazolidone tablets showed good results by the ratio of 4 : 1 or 3: 2 (lactose:starch), and the pressure of $2500kg/cm^2$.

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