The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Carcinoembryonic Antigen Level in Liver Disease

간질환에서의 혈청 Carcinoembryonic Antigen 가(價)

  • Choi, Kyoo-Ok (Department of Radiology, College of Medicine, Yonsei University) ;
  • Kim, Ki-Whang (Department of Radiology, College of Medicine, Yonsei University) ;
  • Park, Chang-Yun (Department of Radiology, College of Medicine, Yonsei University)
  • 최규옥 (연세대학교 의과대학 방사선과학교실) ;
  • 김기황 (연세대학교 의과대학 방사선과학교실) ;
  • 박창윤 (연세대학교 의과대학 방사선과학교실)
  • Published : 1978.12.30
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Abstract

Carcinoembryonic antigen was initially known as tumor specific antigen and had a potential diagnostic value in the detection of digestive tract malignancies. However, subsequent studies showed CEA and CEA-like antigen present in benign disease, particullary in liver. We had collected sera from 58 patients who had liver scan and later were diagnosed clinically and histologically as liver disease. We estimated CEA values and correlations were made with liver function tests in liver cirrhosis cases. The results: 1) The raised plasma carcinoembryonic antigen level were found in 13 (68.4%) of 19 patients in liver cirrhosis, 5(27.8%) of 18 patients in hepatoma, 5(71. %) of 7 patients in chronic active hepatitis, all 3 patients in liver abscesses, 2(66.7%) of 3 patients in liver ablscesses, 2(66.7%) of 3 patients in obstructive biliary disease and none in each one patient of traumatic liver hematoma, subphrenic abscess and clonorchiasis. 2) There is no linear correlation between carcinoembryodic antigen level and liver function tests including serum bilirubin, alkaline phosphatase, SGOT and prothrombin time in liver cirrhosis patients.

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