Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Plants with Liver Protective Activities (II) -Potential Hepatotonic Activities of Plantago asiatica Seed-

강간제(强肝劑)로 사용(使用)된 생약(生藥)의 조사연구(調査硏究) (II) -차전자(車前子)의 강간효과(强肝效果)에 관(關)하여-

  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
  • YunChoi, Hye-Sook (Natural Products Research Institute, Seoul National University)
  • Published : 1978.09.15
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Abstract

Total methanol extract of Plantago asiatica seeds showed significant hepatotonic activities against animal model of hepatitis. The methanol extract was further fractionated with petroleum ether, chloroform, n-butanol and water. Among these fractions, methanol extract and water and chloroform fractions exhibited hepatonic activities, whereas petroleum ether and n-butanol fractions appeared to give rise a rather toxicity. Measurements of serum GOT, GPT and duration of sleeping time induced by hexobarbital after $CCl_4$ intoxication indicated that water fraction showed most potent activities.

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