초록
백삼의 석유에테르추출물(WGpet)은 빵효모의 RNA생합성을 극히 미약하게 촉진시킬 뿐이지만, 백삼의 에탄올추출물(WGpet-alc) 및 홍삼정(RGE)의 성분은 다같이 RNA 생합성을 크게 촉진시킬뿐 아니라, 그 모노누클레오티드의 조성에까지 큰 변화를 일으키는 효과가 있음이 확인되었다. 즉 RGE에 의해 AMP와 CMP는 물론, 특히 UMP가 현저하게 감소된 반면, GMP는 크게 증가되었으며, 그 몰비는 총 모노누클레오티드의 78.5%에 달하였다. 이러한 결과는 인삼성분의 단백질 생합성 촉진효과와도 관련이 있는 퍽 흥미로운 점이라고 하겠다.
It was found that petroleum ether extract of White Ginseng had a very slightly stimulating effect on the RNA biosynthesis of Baker's yeast, while both ethanol extract of White Ginseng(WGpet-alc) and Red Ginseng Extract(RGE) showed a significant stimulating effect on the RNA biosynthesis and its activity to change mononucleotide composition of the yeast RNA was noticeable; RGE induced a remarkable decrease of AMP, CMP and especially of UMP, however a marked increase of GMP, and it was observed that the molar ratio of GMP was 78.5 % of all mononucleotides of the yeast RNA. It is of interest that these results are closely related with the stimulating effect of protein biosynthesis of Baker's yeast cells.