Korean Journal of Microbiology (미생물학회지)

The Microbiological Society of Korea (한국미생물학회)
권호 표지

Studies on the Population of Toxigenic Fungi in Foodstuffs(VIII)

한국 식품중의 유독성 진균에 관한 연구 8

  • Koh, Choon-Myung (Department of Microbiology, Yonsei University College of Medicine) ;
  • Kim, Se-Jong (Department of Microbiology, Yonsei University College of Medicine) ;
  • Cho, She-Hoon (Department of Microbiology, Yonsei University College of Medicine) ;
  • Kim, Sung-Kwang (Department of Microbiology, Yonsei University College of Medicine) ;
  • Lew, Joon (Department of Microbiology, Yonsei University College of Medicine)
  • 고춘명 (연세대학교 의과대학 미생물학교실) ;
  • 김세종 (연세대학교 의과대학 미생물학교실) ;
  • 조세훈 (연세대학교 의과대학 미생물학교실) ;
  • 김성광 (연세대학교 의과대학 미생물학교실) ;
  • 류준 (연세대학교 의과대학 미생물학교실)
  • Published : 1974.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

With an aim to disclose causal factors scably grains intoxications, the screening of toxic Fusaria and the detection of toxic priniciples were performed in respect of cultured cells bioassay with HeLa cells, skin-necrotizing effect, histopathological investigation and also chromatographic analysis sith following results ; 1. Among the fungi, Fusarium sp. F-27, F-63 and F-61 were highly toxic to mice, causing liver injury characterized necrosis and inflammation. 2. HeLa cell culture bioassay demonstrated that the cell of the isolated strains of Fusaria were suspected to produce toxic material (Fusarenon-X). 3. The culture filtrates of Fusarium nivale Fn-2B, F-27, and F-63, were injected subcutaneously, and caused inflammation followed by crust on the skin ICR-mice. 4. The observation method of skin-necrotizing effect to the mice can be used to the screening to the toxin-producing fungi isolated from many fusarial contaminations.

Keywords